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Kamran Hussain

Research

My research focuses on speech brain–computer interfaces, neural population modeling, and computational tools for electrophysiology.

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Papers and preprints

  • A foundation model for brain organoid network dynamics uncovers intrinsic computation and convergent disease phenotypes

    H. E. Schweiger, A. Robbins, S. Hernandez, A. Moreno-Ochando, I. Cline, K. Doganyigit, M. Mouzaya, K. Hussain, Z. P. Pang, J. Duan, S. R. Salama, A. A. Pollen, A. Bhaduri, D. Haussler, M. Teodorescu, M. A. Mostajo-Radji

    bioRxiv preprint · October 13, 2026

    Introduces PULSE, a foundation model trained on over 900 hours of high-density microelectrode array recordings, and uses it to study network development in disease models and how organoid circuits encode information.

  • Implicit Behavioral Decoding from Next-Step Spike Forecasts at Population Scale

    John R. Minnick, Jesus Gonzalez-Ferrer, Kamran Hussain, Jinghui Geng, Ash Robbins, Mohammed A. Mostajo-Radji, David Haussler, Jason Eshraghian, Mircea Teodorescu

    arXiv preprint · May 13, 2026

    Tests whether predicted neural firing rates support behavioral decoding better than raw spike counts under matched temporal context.

  • SpikeProphecy: A Large-Scale Benchmark for Autoregressive Neural Population Forecasting

    John R. Minnick, Jinghui Geng, Kamran Hussain, Jesus Gonzalez-Ferrer, Ash Robbins, Mohammed A. Mostajo-Radji, David Haussler, Jason K. Eshraghian, Mircea Teodorescu

    arXiv preprint · May 13, 2026

    Evaluates spike forecasting across 105 Neuropixels sessions using measures that distinguish temporal and population-pattern performance.

  • SpikeLab: Agentic tools for spike data analysis

    T. van der Molen, L. Cheney, K. Hussain, O. Brahme, A. Robbins, M. Lim, A. Spaeth, J. Geng, D. F. Parks, K. S. Kosik, M. Teodorescu, D. Haussler, T. Sharf

    bioRxiv preprint · April 29, 2026

    Combines a neural-data analysis library with structured agent workflows for reproducible electrophysiology analysis.

Talks

  • Advancing speech BCIs towards conversational speeds in people with paralysis

    Conference talk · 11th International BCI Meeting, Research Session 1 · June 3, 2025 · Banff, Canada

  • Generative Foundation Model for Cortical Organoid Electrophysiology

    Talk · UCSC ACM Undergraduate Research Conference · May 2024 · Santa Cruz, CA

Posters

  • Towards Conversational Rate Speech Brain–Computer Interfaces

    Poster · Simons Foundation SURFiN Symposium · April 2025 · New York, NY

  • Does Speech Rate Matter for Intracortical Speech BCIs?

    Poster · Wu Tsai Neurosciences Institute Annual Symposium · October 2024 · Stanford, CA

  • Building a Baseline for Neural Activity Prediction and Analysis: Machine Learning on HD-MEA Data

    Poster · UCSC ACM Undergraduate Research Conference · May 2024 · Santa Cruz, CA

  • LLM Automated Control of an IoT Integrated System

    Poster · UCSC ACM Undergraduate Research Conference · May 2024 · Santa Cruz, CA